Hen lysozyme amyloid fibrils induce aggregation of erythrocytes and lipid vesicles

Chaudhary, Nitin ; Nagaraj, Ramakrishnan (2009) Hen lysozyme amyloid fibrils induce aggregation of erythrocytes and lipid vesicles Molecular and Cellular Biochemistry, 328 (1-2). pp. 209-215. ISSN 0300-8177

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Official URL: http://www.springerlink.com/content/f23j2678m3n235...

Related URL: http://dx.doi.org/10.1007/s11010-009-0091-8

Abstract

We have studied the interaction of hen egg white lysozyme (HEWL) amyloid fibrils with human erythrocytes and lipid vesicles. The fibrils caused extensive aggregation of human erythrocytes and lipid vesicles without any significant lysis. The membrane activity of HEWL fibrils suggests that the interaction of lysozyme fibrils with cellular membranes could be a contributing factor under disease conditions.

Item Type:Article
Source:Copyright of this article belongs to Springer-Verlag.
Keywords:Lysozyme Fibrils; Membrane Interaction; Erythrocytes; Lipid Vesicles
ID Code:24196
Deposited On:29 Nov 2010 10:14
Last Modified:23 Jan 2011 17:30

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