Organo-lithiation and halogen metal exchange reactions in organic synthesis-an anomolous aromatic substitution via halogen-metal exchange

Narasimhan, N. S. ; Joshi, R. R. (1988) Organo-lithiation and halogen metal exchange reactions in organic synthesis-an anomolous aromatic substitution via halogen-metal exchange Proceedings of the Indian Academy of Sciences - Chemical Sciences, 100 (2-3). pp. 205-215. ISSN 0253-4134

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Official URL: http://www.ias.ac.in/j_archive/chemsci/100/1/205-2...

Related URL: http://dx.doi.org/10.1007/BF02839448

Abstract

Synthesis via organo-lithium compounds is reviewed. An anomalous aromatic substitution via halogen-metal exchange is described. Here, the substitution does not occur at the position where the halogen was present; but at an alternate position. A mechanism is advanced, in which the halogen-metal exchange is proposed as being faster than the hydrogen(acidic)-metal exchange.

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Sciences.
Keywords:Organolithiation; Metal-halogen Exchange; Anomalous Substitution and Mechanism
ID Code:24172
Deposited On:29 Nov 2010 10:17
Last Modified:17 May 2016 07:54

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