Aza-annulation of polarized N,S- and N,N-ketene acetals with itaconic anhydride: synthesis of novel functionalized 1,2,3,4-tetrahydro-2-pyridones and related azabicycles

Chakrabarti, Sriparna ; Panda, Kausik ; Misra, Nimesh C. ; Ila, Hiriyakkanavar ; Junjappa, Hiriyakkanavar (2005) Aza-annulation of polarized N,S- and N,N-ketene acetals with itaconic anhydride: synthesis of novel functionalized 1,2,3,4-tetrahydro-2-pyridones and related azabicycles Synlett, 2005 (9). pp. 1437-1441. ISSN 0936-5214

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-2005-868491

Abstract

Synthesis of novel highly functionalized 2-oxo-(1,2,3,4-tetrahydropyridin-3-yl)acetic acids has been described via aza-annulation of both acyclic and cyclic α -oxo- and α -nitro-N,S- and -N,N-ketene acetals with itaconic anhydride.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers Inc.
Keywords:Alkaloids; Annulation; Esters; Heterocycles; Lactams; Michael Addition; Nitriles
ID Code:24086
Deposited On:29 Nov 2010 10:28
Last Modified:22 Feb 2011 04:51

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