Ray, Pradip K. ; Banerjee, Ranajit K. ; Datta, Asoke G. (1973) A new biochemical effect of erythropoietin Biochemical and Biophysical Research Communications, 52 (4). pp. 1320-1328. ISSN 0006-291X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000629...
Related URL: http://dx.doi.org/10.1016/0006-291X(73)90645-1
Abstract
Erythropoietin stimulated lactoperoxidase (LP) or horseradishperoxidase (HRP) catalyzed iodination of tyrosine, the stimulation being more pronounced in case of LP. The diiodotyrosine (DIT) formation was stimulated more than MIT formation although the total quantity of DIT formed was less than MIT. Both sheep plasma erythropoietin and human urinary erythropoietin exhibited the above phenomenon and the stimulatory effects were directly propertional to their potencies. Preincubation of erythropoietin with neuraminidase abolished its stimulatory effect. Other glycoprotein hormones like thyrotropic hormone (TSH) and human chorionic gonadotrophin (HCG) did not stimulate the above system.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 23604 |
| Deposited On: | 26 Nov 2010 08:40 |
| Last Modified: | 31 May 2011 04:27 |
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