Ranganathan, Darshan ; Samant, Manoj P. ; Nagaraj, Ramakrishnan ; Bikshapathy, E. (2002) Design, synthesis and membrane ion transport properties of cystine- and serine-based cyclo-4-oxa-heptane-1,7-bisamides Tetrahedron Letters, 43 (29). pp. 5145-5147. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/S0040-4039(02)00979-6
Abstract
A new class of cyclobisamides, having the general profile of amino acid (cystine or serine)-ether composites, as potentially efficient ion transporters has been designed and synthesized. In model membranes, the adamantane harboring composites exhibited 57-66% of gramicidin A activity in ion transport.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Amino Acid; Cyclobisamide; Gramicidin A; Ionophore; Macrocycle; Membrane |
| ID Code: | 23509 |
| Deposited On: | 25 Nov 2010 13:13 |
| Last Modified: | 24 Jan 2011 11:01 |
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