Ghosh, Prahlad C. ; Bachhawat, Bimal K. (1992) Role of surface glycolipids-natural or synthetic origin on the biodistribution of liposomes Journal of Liposome Research, 2 (3). pp. 369-382. ISSN 0898-2104
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Official URL: http://www.informahealthcare.com/doi/abs/10.3109/0...
Related URL: http://dx.doi.org/10.3109/08982109209010215
Abstract
Various sugar residues were incorporated on the surface of liposomes and its effect on the biodistribution and therapeutic importance were discussed here. Galactosylated liposomes were preferentially taken up by liver parenchymal cells whereas mannosylated liposomes were mainly localized in non-parenchyma1 cells. On the other hand, incorporation of dextran on the surface results in increased circulatory half-life of liposomes. The potential application of such liposomes as a carrier of drugs in the diseased condition is also discussed.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Informa Healthcare. |
| ID Code: | 2278 |
| Deposited On: | 07 Oct 2010 11:38 |
| Last Modified: | 12 May 2011 11:27 |
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