Biosynthesis of (+)-,(-)- and (±)-tetrahydropalmatines

Bhakuni, Dewan S. ; Jain, Sudha ; Gupta, Sandeep (1984) Biosynthesis of (+)-,(-)- and (±)-tetrahydropalmatines Tetrahedron, 40 (9). pp. 1591-1593. ISSN 0040-4020

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4020(01)91809-5

Abstract

Specific incorporation of didehydroreticuline and reticuline into (±)- (+)-, and (-)-tetrahydropalmatines in Cocculus laurifolius and of (R)- and (S)-reticulines into (R)- and (S)-tetrahydropalmatines respectively has been demonstrated. Feeding of[l-3H, 4'-methoxy-14C]reticuline suggested that reticuline was not converted in the plants into didehydroreticuline and racemisation of optically active forms of tetrahydropalmatine did not take place via dehydrotetrahydropalmatine.

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