Optofluidic stretching of RBCs using single optical tweezers

Mohanty, S. K. ; Uppal, A. ; Gupta, P. K. (2008) Optofluidic stretching of RBCs using single optical tweezers Journal of Biophotonics, 1 (6). pp. 522-525. ISSN 1864-063X

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/jbio.20...

Related URL: http://dx.doi.org/10.1002/jbio.200810001

Abstract

Our previous studies demonstrated a huge difference in rotational speed of trapped red blood cells under diseased condition, which was presumably attributed to change in viscoelastic properties. Here, we report use of single optical tweezers combined with viscous drag for stretching of the trapped cell. Significant differences were observed in the measured viscoelastic parameters of fresh and aged/malaria-infected RBCs under hypotonic condition. The technique was also found to provide information about adhesion properties of RBCs.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons, Inc.
Keywords:87.80.Cc; 87.80.-y
ID Code:22220
Deposited On:23 Nov 2010 08:24
Last Modified:02 Jun 2011 06:38

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