Farooqui, A. A. ; Bachhawat, B. K. (1971) The regional distribution, age dependent variation and species differences of brain arylsulphatases Journal of Neurochemistry, 18 (4). pp. 635-646. ISSN 0022-3042
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Official URL: http://www3.interscience.wiley.com/journal/1196911...
Related URL: http://dx.doi.org/10.1111/j.1471-4159.1971.tb11994.x
Abstract
The relative proportions of arylsulphatase A and B were determined by the method of Baum, Dodgson and Spencer (1959) in brains of various animal species and it was found that there was a considerable variation in the concentration of these two enzymes. Arylsulphatase A and B of various animal species including rat, man, monkey, sheep and chicken were partially separated using zinc acetate fractionation procedure and gel electrophoresis. The chicken brain arylsulphatase A had a similar electrophoretic mobility to that of arylsulphatase B of other species. Further, chicken brain arylsulphatase A precipitated at a zinc acetate concentration of 0005 M, a condition under which arylsulphatase B from the brain of other species precipitated. Kinetic properties such as Km value and inhibitory effect of sulphite and phosphate ions indicated that chicken brain arylsulphatase A was similar to arylsulphatase A of other species. The results on regional distribution of arylsulphatase A and B activities in monkey brain and in developing rat brain suggest a relationship between arylsulphatase A and sulphatides and arylsulphatase B and mucopolysaccharides.
Item Type: | Article |
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Source: | Copyright of this article belongs to International Society for Neurochemistry. |
ID Code: | 2178 |
Deposited On: | 08 Oct 2010 07:39 |
Last Modified: | 16 May 2016 13:12 |
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