Ravindranath, N. ; Moudgal, N. R. (1990) Luteal-phase defect induced by deprivation of FSH at a specific period of the follicular phase prevents pregnancy in the bonnet monkey (Macaca radiata) Journal of Reproduction and Fertility, 88 (1). pp. 25-30. ISSN 0022-4251
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Official URL: http://www.reproduction-online.org/cgi/content/abs...
Related URL: http://dx.doi.org/10.1530/jrf.0.0880025
Abstract
Female bonnet monkeys were injected i.v. with 25 µl antiserum to FSH on Days 5, 6 or 7 of the cycle: the length of the luteal phase was shortened but there was no alteration in cycle length. Proven fertile females (N = 6) were caged throughout the period of the experiment (6 cycles) with proven fertile males and treated with 25 µl FSH antiserum on Day 7 of each of 3 successive cycles. Out of 18 cycle exposures during the treatment phase, 17 were ovulatory, but no pregnancies occurred. In the post-treatment phase, 5 monkeys became pregnant within 3 cycle exposures. These results show that it is possible to render female monkeys infertile by creating luteal insufficiency and this can be achieved repeatedly in a reproducible manner by depriving the cyclic females of FSH support on Day 7 of consecutive cycles.
Item Type: | Article |
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Source: | Copyright of this article belongs to Society for Reproduction and Fertility. |
Keywords: | Monkey; Ovary; Follicular Phase; Luteal Phase Defect; Pregnancy |
ID Code: | 21707 |
Deposited On: | 22 Nov 2010 10:59 |
Last Modified: | 17 May 2016 05:53 |
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