Moudgal, N. R. (1962) Immunochemical investigation of a biologically active core obtained from chymotryptic digestion of bovine growth hormone General and Comparative Endocrinology, 2 (2). pp. 236-239. ISSN 0016-6480
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/001664...
Related URL: http://dx.doi.org/10.1016/0016-6480(62)90008-4
Abstract
The differences in antigenicity between bovine growth hormone and a biologically active core obtained from a chymotryptic digest of bovine growth hormone have been investigated in the rabbit and the guinea pig. A decrease in the antigenic potency of bovine growth hormone has been shown to result from chymotryptic digestion. Under essentially the same conditions of immunization, a greater amount of an active core than of untreated hormone is required to immunize both the rabbit and the guinea pig. The quantitative aspects of the cross reaction between the parent molecule and the active core have been investigated in detail and the results discussed. The active core has been shown to contain at least three antigenic components.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 21669 |
| Deposited On: | 22 Nov 2010 11:04 |
| Last Modified: | 08 Jun 2011 11:23 |
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