Effect of ICSH on early pregnancy in hypophysectomized pregnant rats

Moudgal, N. R. (1969) Effect of ICSH on early pregnancy in hypophysectomized pregnant rats Nature, 222 (5190). pp. 286-287. ISSN 0028-0836

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Official URL: http://www.nature.com/nature/journal/v222/n5190/ab...

Related URL: http://dx.doi.org/10.1038/222286a0

Abstract

Moudgal and co-workers recently reported that the administration to intact pregnant rats of rabbit antiserum ovine interstitial cell stimulating hormone (ICSH) on any one day between the eighth and twelfth days of pregnancy resulted in resorption of foetuses and termination of pregnancy. This effect was readily reversed by the simultaneous administration of progesterone but not by oestradiol-17β. These observations suggested that ICSH was involved in progesterone synthesis and as such is a luteotropic factor in the rat.

Item Type:Article
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Deposited On:22 Nov 2010 11:08
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