Majumder, Partha P. ; Nath, Swapan K. (1992) Statistical analysis of family data on complex disorders in man Journal of Genetics, 71 (3). pp. 89-103. ISSN 0022-1333
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Official URL: http://www.ias.ac.in/jarch/jgenet/71/89.pdf
Related URL: http://dx.doi.org/10.1007/BF02927890
Abstract
A genetic model is discussed for recessively inherited disorders that do not follow a single-locus Mendelian pattern of inheritance. Further complexity arising from variable age of onset is also discussed. Methods of statistical analysis of family data using the likelihood principle are described for such complex disorders. The methods are exemplified using data on families of prelingual deafness and vitiligo.
| Item Type: | Article |
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| Source: | Copyright of this article belongs to Indian Academy of Sciences. |
| Keywords: | Segregation Analysis; Autosomal Recessive; Multiple Loci; Variable Onset Age; Prelingual Deafness; Vitiligo |
| ID Code: | 21380 |
| Deposited On: | 20 Nov 2010 13:00 |
| Last Modified: | 17 May 2016 05:35 |
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