Prema Kumar, R. ; Ravindranath, S. D. ; Vaidyanathan, C. S. ; Appaji Rao, N. (1972) Mechanism of hydroxylation of aromatic compounds: II. Evidence for the involvement of superoxide anions in enzymatic hydroxylations Biochemical and Biophysical Research Communications, 49 (6). pp. 1422-1426. ISSN 0006-291X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000629...
Related URL: http://dx.doi.org/10.1016/0006-291X(72)90497-4
Abstract
The mechanism of hydroxylation reactions catalyzed by m-hydroxybenzoate-4-hydroxylase and anthranilate hydroxylase from Aspergillus niger was investigated using superoxide dismutase from ovine erythrocytes. Inclusion of superoxide dismutase in the assay mixtures of the two enzymes resulted in complete inhibition of the hydroxylation reaction, indicating the possible involvement of superoxide anions (O2-) in these reactions.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 21203 |
| Deposited On: | 20 Nov 2010 09:03 |
| Last Modified: | 14 Jun 2011 10:26 |
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