Maitra, Uday ; Babu, Ponnusamy (2003) First synthesis of phosphonobile acids and preliminary studies on their aggregation properties Steroids, 68 (5). pp. 459-463. ISSN 0039-128X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00391...
Related URL: http://dx.doi.org/10.1016/S0039-128X(03)00051-5
Abstract
The synthesis of three novel phosphonobile acids from natural bile acids is reported. The CMC of phosphonodeoxycholic acid (PDCA) at pH 8.2 was found to be lower than that of the parent deoxycholic acid (DCA). PDCA micelles were also found to have higher microviscosity compared to DCA micelles, suggesting higher hydrophobicity and tighter packing in the interior of PDCA micelles. PDCA aggregated further to form an aqueous gel at pH 4.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Aggregation; Arbuzov Reaction; Bile Acids; Aqueous Gel; Phosphonic Acids |
| ID Code: | 21182 |
| Deposited On: | 20 Nov 2010 08:56 |
| Last Modified: | 20 Nov 2010 08:56 |
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