Bhakuni, Vinod ; Roy, Raja (1994) Interaction of trichloroethylene with phosphatidylcholine and its localization in the phosphatidylcholine vesicles: a 1H-NMR study Biochemical Pharmacology, 47 (8). pp. 1461-1464. ISSN 0006-2952
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000629...
Related URL: http://dx.doi.org/10.1016/0006-2952(94)90349-2
Abstract
The interaction of trichloroethylene, an inhalation general anesthetic, with egg yolk phosphatidylcholine (EYPC) and its localization in small unilamellar vesicles (SUV) has been studied by Nuclear Magnetic Resonance. These studies demonstrate that inhalation anesthetic can interact nonspecifically with lipid molecules. Furthermore, it suggests that the action of inhalation anesthetics is directed primarily to the interfacial region of the lipid membrane.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Anesthetic; Temperature; Nuclear Overhauser Enhancement; Interface; Nonspecific Interactions; T1 Measurements |
| ID Code: | 21049 |
| Deposited On: | 20 Nov 2010 09:18 |
| Last Modified: | 20 Nov 2010 09:18 |
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