Gandhi, B. M. ; Irshad, M. ; Acharya, S. K. ; Joshi, Y. K. ; Tandon, B. N. (1988) Evidence of ongoing virus multiplication in type B fulminant hepatitis Journal of Gastroenterology and Hepatology, 3 (2). pp. 139-142. ISSN 0815-9319
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Official URL: http://www3.interscience.wiley.com/journal/1194586...
Related URL: http://dx.doi.org/10.1111/j.1440-1746.1988.tb00229.x
Abstract
The presence of HBeAg- and HBV-specific DNA-polymerase (DNA-P) activity-regarded as markers of HBV multiplication-were studied in 40 patients with fulminant hepatitis B within 1-5 days of the onset of hepatic encephalopathy. HBeAg and DNA-P were detected in three (7 %) and 21 (51%) of the patients respectively. Only three (7%) were positive for anti-HBs. DNA-P activity was present in 38.1 % even 10 days after the appearance of icterus. Present findings confirm an ongoing HBV multiplication in about half of the patients of fulminant hepatitis B.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons, Inc. |
| Keywords: | DNA-polymerase Activity; Fulminant Hepatitis B; Hepatitis B; Hepatitis B e Antigen; Hepatitis B Virus; |
| ID Code: | 208 |
| Deposited On: | 17 Sep 2010 09:01 |
| Last Modified: | 12 May 2011 04:15 |
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