Tobacco mosaic virus protein induces fusion of liposome membranes

Banerjee, Sunanda ; Vandenbranden, Michel ; Ruysschaer, Jean-Marie (1981) Tobacco mosaic virus protein induces fusion of liposome membranes Biochimica et Biophysica Acta: Biomembranes, 646 (2). pp. 360-364. ISSN 0005-2736

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000527...

Related URL: http://dx.doi.org/10.1016/0005-2736(81)90345-X

Abstract

The fusogenic properties of tobacco mosaic virus (TMV) coat protein were investigated. Tobacco mosaic virus protein induces membrane fusion of a population of L-α-dimyristoylphosphatidylcholine (DMPC) and d L-α-dipalmitoylphosphatidylcholine (DPPC) vesicles giving rise to large particles as seen by a drastic absorbance increase of the liposomal solution. Differential scanning calorimetry spectra demonstrate complete mixing of the acyl chains of the lipids during fusion. Electron micrographs indicate that the fused entities are multilamellar.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Tobacco Mosaic Virus; Viral Protein; Liposome; Fusion
ID Code:20786
Deposited On:20 Nov 2010 13:33
Last Modified:20 Nov 2010 13:33

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