Rama Rao, A.V. ; Chakraborty, T. K. ; Sankaranayanan, D. ; Purandare, A. V. (1991) Studies directed towards the synthesis of immunosuppressive agent FK-506: synthesis of the entire top-half Tetrahedron Letters, 32 (4). pp. 547-550. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/S0040-4039(00)79493-7
Abstract
An efficient approach has been developed to construct the entire TOP-HALF of FK-506 involving Grignard reaction of a C-29 bromide with a C-27 methylketo fragment.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 20641 |
| Deposited On: | 20 Nov 2010 13:48 |
| Last Modified: | 20 May 2011 11:40 |
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