Chakraborty, Tushar K. ; Ghosh, Subhash ; Dutta, Shantanu (2001) Studies directed towards the synthesis of stevastelins-a macrolactonization approach to stevastelin B Tetrahedron Letters, 42 (30). pp. 5085-5088. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/S0040-4039(01)00893-0
Abstract
A synthetic approach towards the cyclic depsipeptide immunosuppressant stevastelin B, based on the stereoselective synthesis of its propionate-derived fatty acid segment 6 that was coupled with the tripeptide 7 leading to the advanced stage acyclic intermediate 5, is described. In spite of our best efforts, the crucial macrolactonization reaction was not successful.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 20604 |
| Deposited On: | 20 Nov 2010 13:53 |
| Last Modified: | 22 May 2011 15:49 |
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