Chakraborty, Tushar K. ; Tapadar, Subhasish (2003) Synthesis of (+)-prelactone B Tetrahedron Letters, 44 (12). pp. 2541-2543. ISSN 0040-4039
Full text not available from this repository.
Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/S0040-4039(03)00326-5
Abstract
Radical-mediated opening of a trisubstituted epoxy alcohol using cp2TiCl was followed by diastereoselective reduction of the resulting product with a centrally located methylene group, flanked on both sides by two chiral hydroxyl-bearing carbons, to build all the three chiral centers of (+)-prelactone B 1 in their desired stereochemistries leading to the total synthesis of the molecule.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Prelactone B; Sharpless Kinetic Resolution; Epoxide Opening; 2-methyl-1,3-diol |
| ID Code: | 20586 |
| Deposited On: | 20 Nov 2010 14:16 |
| Last Modified: | 22 May 2011 15:11 |
Repository Staff Only: item control page
