Chakraborty, Tushar Kanti ; Mohan, Bajjuri Krishna (2006) Studies directed towards the synthesis of antascomicin A: stereoselective synthesis of the C1-C21 fragment of the molecule Tetrahedron Letters, 47 (29). pp. 4999-5002. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.05.113
Abstract
A stereoselective synthesis of the C1-C21 fragment of the non-immunosuppressive immunophilin-binding natural product, antascomicin A was achieved using, as key steps, highly stereoselective Aldol reactions to build the C1-C17 fragment and a Nozaki-Hiyama-Kishi reaction to couple it with the remaining C18-C21 moiety.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
Keywords: | Antascomicin; Immunosuppressant; FKBP12 Binding Ligand; Takai Reaction |
ID Code: | 20512 |
Deposited On: | 20 Nov 2010 14:23 |
Last Modified: | 01 Feb 2011 08:47 |
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