Chakraborty, Tushar K. ; Srinivasa Rao, K. ; Udaya Kiran, M. ; Jagadeesh, B. (2008) Nucleation of the β-hairpin structure in a linear hybrid peptide containing α-, β- and γ-amino acids Tetrahedron Letters, 49 (14). pp. 2228-2231. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2008.02.048
Abstract
Synthesis and conformational studies of a short linear peptide containing a pyrrole amino acid (1, Paa) and a furan amino acid (2, Faa), namely Boc-hGly-Faa-d-Pro-Gly-Paa-hGly-Faa-OMe (3), were carried out in which it was established that peptide 3 adopted a well-defined β-hairpin structure in DMSO-d6.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
Keywords: | Peptide Mimetics; Pyrrole Amino Acid; Furan Amino Acid; Hydrogen Bonding; Conformation; NMR |
ID Code: | 20457 |
Deposited On: | 20 Nov 2010 14:29 |
Last Modified: | 22 May 2011 14:47 |
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