Ti(III)-mediated radical cyclization of β-aminoacrylate containing epoxy alcohol moieties: synthesis of highly substituted azacycles

Chakraborty, Tushar Kanti ; Samanta, Rajarshi ; Roy, Saumya ; Sridhar, Balasubramanian (2009) Ti(III)-mediated radical cyclization of β-aminoacrylate containing epoxy alcohol moieties: synthesis of highly substituted azacycles Tetrahedron Letters, 50 (26). pp. 3306-3310. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2009.02.063

Abstract

Ti(III)-mediated radical cyclization of β-aminoacrylate containing 2,3-epoxy alcohol moieties led to the formation of highly substituted piperidine and pyrrolidine rings. The pyrrolidine ring system was then transformed into an indolizidine framework present in many natural products.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Piperidine; Pyrrolidine; Indolizidine; Ti(III)-mediated Epoxide Opening; Radical Cyclization; β-aminoacrylates
ID Code:20431
Deposited On:20 Nov 2010 14:31
Last Modified:17 May 2016 04:46

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