Prevalence of anti-hepatitis E virus antibodies in different Indian animal species

Arankalle, V. A. ; Joshi, M. V. ; Kulkarni, A. M. ; Gandhe, S. S. ; Chobe, L. P. ; Rautmare, S. S. ; Mishra, A. C. ; Padbidri, V. S. (2001) Prevalence of anti-hepatitis E virus antibodies in different Indian animal species Journal of Viral Hepatitis, 8 (3). pp. 223-227. ISSN 1352-0504

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Official URL: http://onlinelibrary.wiley.com/doi/10.1046/j.1365-...

Related URL: http://dx.doi.org/10.1046/j.1365-2893.2001.00290.x

Abstract

Prevalence of IgG antibodies to hepatitis E virus (IgG-anti-HEV) was determined among different animal species from India. Seropositivity varied from 4.4% to 6.9% in cattle, 54.6-74.4% in pigs and 2.1-21.5% in rodents. Of the 44 dogs screened, 10 were positive (22.7%). None of the 250 goat sera tested were found to be anti-HEV positive. Among rodents, over 50% serum samples collected in 1985 from Bandicota bengalensis were positive for anti-HEV antibodies. No evidence of HEV infection was obtained following experimental inoculation of an Indian strain (AKL-90) of HEV into anti-HEV negative pigs and goats. The results document varied prevalence of anti-HEV antibodies in different animal species from India and of inability of Indian pigs and goats to support replication of at least one human strain of HEV.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons, Inc.
Keywords:Animals; Anti-hepatitis E Antibodies; Experimental Transmission; India
ID Code:19915
Deposited On:22 Nov 2010 11:40
Last Modified:06 Jun 2011 11:41

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