Bawari, M. ; Babu, G. Nagesh ; Ali, M. M. ; Misra, U. K. (1995) Effect of neonatal monosodium glutamate on the activities of glutamate dehydrogenase and aminotransferases in the circumventricular organs of rat brain Amino Acids, 8 (4). pp. 393-395. ISSN 0939-4451
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Official URL: http://www.springerlink.com/content/wl115x1605r521...
Related URL: http://dx.doi.org/10.1007/BF00806557
Abstract
Glutamate (Glu) the major amino acid in mammalian brain and most dietary proteins possesses neurotransmitter as well as neurotoxic properties. We administered monosodium glutamate (MSG) 4 mg/g bwt, sc on postnatal day (PND) 1 through 10 to rats on alternate days or daily and sacrificed them on PND 45 or PND 90 respectively. The activities of glutamate dehydrogenase and aminotransferases were evaluated in the circumventricular organs of brain. Results show that neonatal MSG produces alterations in glutamate metabolism in blood-brain-barrier deficient regions.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer-Verlag. |
| Keywords: | Amino Acids; Monosodium Glutamate; Glutamate Dehydrogenase; Aminotransferases |
| ID Code: | 19900 |
| Deposited On: | 22 Nov 2010 11:42 |
| Last Modified: | 11 Jun 2011 09:55 |
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