Kalita, J. ; Patel, N. S. ; Misra, U. K. (2008) Magnetic resonance imaging may simulate progressive multifocal leucoencephalopathy in a patient with chronic lymphocytic leukemia after fludarabine therapy Annals of Indian Academy of Neurology, 11 (2). pp. 114-115. ISSN 0972-2327
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Official URL: http://www.annalsofian.org/article.asp?issn=0972-2...
Related URL: http://dx.doi.org/10.4103/0972-2327.41880
Abstract
A 60-year-old male with chronic lymphatic leukemia (CLL) after 6 months of fludarabine therapy was admitted with status epilepticus and developed left hemiplegia. His magnetic resonance imaging revealed multiple T2 hyperintense lesions in the right frontal and left parieto-occipital lesion, simulating progressive multifocal leucoencephalopathy (PML). Cerebrospinal fluid Polymerase Chain Reaction (PCR) for JC virus was negative. We suggest the possible role of fludarabine in producing PML-like lesions in patients with Chronic Lymphocytic Leukemia (CLL).
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Medknow Publications. |
| ID Code: | 19803 |
| Deposited On: | 22 Nov 2010 11:53 |
| Last Modified: | 08 Jun 2011 11:36 |
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