Sayem Alam, Md. ; Kabir-ud-Din, Kabir-ud-Din ; Mandal, Asit Baran (2010) Thermodynamics of some amphiphilic drugs in presence of additives Journal of Chemical & Engineering Data, 55 (7). pp. 2630-2635. ISSN 0021-9568
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Official URL: http://pubs.acs.org/doi/abs/10.1021/je900749a
Related URL: http://dx.doi.org/10.1021/je900749a
Abstract
In the present paper, we report the thermodynamics of the four amphiphilic drugs (two antidepressants, amitriptyline hydrochloride and imipramine hydrochloride, and two phenothiazines, chlorpromazine hydrochloride and promethazine hydrochloride) in the presence of additives [NaCl, cetyltrimethylammonium bromide (CTAB), polyethylene glycol t-octylphenyl ether (TX-100)] and evaluated Gibbs energies [at the air/water interface (Gmin(s)), the standard Gibbs energy change of micellization (ΔmicG0), the standard Gibbs energy change of adsorption (ΔadsG0), and the excess free energy change of micellization (ΔGex)].
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 19652 |
| Deposited On: | 22 Nov 2010 12:09 |
| Last Modified: | 01 Mar 2011 03:17 |
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