Mandal, Chitra ; Chatterjee, Mitali ; Sinha, Diviya (2000) Investigation of 9-o-acetylated sialoglycoconjugates in childhood acute lymphoblastic leukaemia British Journal of Haematology, 110 (4). pp. 801-812. ISSN 0007-1048
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Official URL: http://onlinelibrary.wiley.com/doi/10.1046/j.1365-...
Related URL: http://dx.doi.org/10.1046/j.1365-2141.2000.02105.x
Abstract
Modern treatment protocols of childhood acute lymphoblastic leukaemia (ALL) utilize the biological and clinical features of the disease to tailor the intensity of therapy to the risk of relapse by evaluation of minimal residual disease (MRD) using several molecular techniques. To minimize the likelihood of false negative results, tandem application of at least two methods for detection of MRD is currently recommended. To address this question, the present review deals with the recently evolved information reported by our group regarding the presence of O-acetylated sialoglycoconjugates (O-AcSGs) in childhood ALL and their potential as novel biomarkers for monitoring the disease.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to British Society for Haematology. |
| Keywords: | Sialic Acids; 9-O-acetylated Sialoglycoconjugates; Anti-9-O-acetylated Sialoglycoconjugates; Minimal Residual Disease (MRD); Childhood Acute Lymphoblastic Leukaemia (ALL) |
| ID Code: | 18969 |
| Deposited On: | 25 Nov 2010 14:40 |
| Last Modified: | 25 Nov 2010 14:40 |
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