Arif, Mohammed ; Selvi, B. Ruthrotha ; Kundu, Tapas K. (2010) Lysine acetylation: the tale of a modification from transcription regulation to metabolism Chembiochem, 11 (11). pp. 1501-1504. ISSN 1439-4227
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/cbic.20...
Related URL: http://dx.doi.org/10.1002/cbic.201000292
Abstract
Reversible lysine acetylation is an important modification involved in the regulation of gene expression. Acetyl-CoA and NAD+ are major determinants of this modification, NAD+ levels being regulated by the cellular redox status. Recent reports have shown that lysine acetylation also regulates metabolic processes, thus linking the central metabolic process to gene expression.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons, Inc. |
| Keywords: | Epigenetic Therapy; Gene Expression; Lysine Acetylation; Metabolism; NAD+ |
| ID Code: | 18963 |
| Deposited On: | 25 Nov 2010 14:41 |
| Last Modified: | 04 Jun 2011 09:01 |
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