Synthesis of C2-symmetric bis-indolyl sulfones

Mitra, Tapobrata ; Das, Sanket ; Basak, Amit (2009) Synthesis of C2-symmetric bis-indolyl sulfones Tetrahedron Letters, 50 (42). pp. 5846-5849. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2009.08.001

Abstract

A new class of C2-symmetric bis-indole derivatives with 2,2-linkage has been synthesized from bis-propargyl sulfones. The method involves treatment of the sulfones with catalytic amount of triethylamine to form the indole derivatives presumably via the intramolecular Michael addition to the intermediate bis-allenic sulfones. Interestingly, the expected Garratt-Braverman pathway was not followed.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:1793
Deposited On:05 Oct 2010 12:00
Last Modified:12 Jan 2011 11:38

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