Das, Sanket ; Basak, Amit (2009) Design and synthesis of bisenediyne bissulfones and their reactivity under basic condition Bioorganic & Medicinal Chemistry Letters, 19 (10). pp. 2815-2818. ISSN 0960-894X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S09608...
Related URL: http://dx.doi.org/10.1016/j.bmcl.2009.03.094
Abstract
A new class of bisenediyne bis sulfones has been synthesized. These molecules underwent cycloaromatization under basic conditions via isomerization to allene and were able to cleave ds-stranded plasmid DNA.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Bisenediyne Bissulphone; Allene; Cycloaromatization; DNA Cleavage; Bergman Cyclization; Myers-saito Cyclization |
| ID Code: | 1790 |
| Deposited On: | 05 Oct 2010 12:00 |
| Last Modified: | 12 Jan 2011 12:06 |
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