L-Proline-mediated one-pot synthesis of 3-exomethylene β-lactams via kinugasa reaction

Basak, Amit ; Ghosh, Subhash Chandra (2004) L-Proline-mediated one-pot synthesis of 3-exomethylene β-lactams via kinugasa reaction Synlett, 2004 (9). pp. 1637-1639. ISSN 0936-5214

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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...

Related URL: http://dx.doi.org/10.1055/s-2004-829097

Abstract

Synthetically important 3-exomethylene β-lactams 4a-f were obtained in a single step via Cu(I)-mediated cycloaddition-between propargyl alcohol/butyn-2-ol and nitrones 2a-d, in the presence of l-proline (Kinugasa reaction).

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers Inc.
Keywords:Kinugasa Reaction; β-lactams; Isoxazoline; Amino Acids; Proline
ID Code:1715
Deposited On:05 Oct 2010 12:05
Last Modified:13 Jan 2011 10:50

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