Vyavahare, N. R. ; Kulkarni, M. G. ; Mashelkar, R. A. (1990) Zero order release from glassy hydrogels. II. Matrix effects Journal of Membrane Science, 54 (1-2). pp. 205-220. ISSN 0376-7388
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S03767...
Related URL: http://dx.doi.org/10.1016/S0376-7388(00)82080-3
Abstract
A series of copolymers of 2 -hydroxyethyl methacrylate (HEMA) with a hydrophobic monomer, methoxyethyl methacrylate (MEMA), and a hydrophilic monomer, methoxyethoxyethyl methacrylate (MEEMA), was evaluated as matrices for the release of benzoic acid and theophylline. The results are discussed in the context of the criteria developed in the literature for zero order release from glassy hydrogels. Release of theophylline from a p (HEMA-MEMA) matrix containing 22% MEMA followed zero order kinetics. Benzoic acid was released at constant rate from all the matrices.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 17122 |
| Deposited On: | 16 Nov 2010 08:26 |
| Last Modified: | 04 Jun 2011 08:30 |
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