Design, synthesis and biological activity of novel enediynyl monocyclic β-lactams

Basak, Amit ; Khamrai, Uttam Kumar (1996) Design, synthesis and biological activity of novel enediynyl monocyclic β-lactams Tetrahedron Letters, 37 (14). pp. 2475-2478. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/004040...

Related URL: http://dx.doi.org/10.1016/0040-4039(96)00297-3

Abstract

Monocyclic β-lactams 1-3 substituted at C-4 with enediyne moiety have been synthesized via Pd(0) mediated coupling reaction. Their antibacterial activity against ampicillin-resistant E. coli have been tested.

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