Balraju, V. ; Iqbal, Javed (2006) Synthesis of cyclic peptides constrained with biarylamine linkers using buchwald-hartwig C-N coupling Journal of Organic Chemistry, 71 (23). pp. 8954-8956. ISSN 0022-3263
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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo061366i
Related URL: http://dx.doi.org/10.1021/jo061366i
Abstract
In this paper, we describe the synthesis of conformationally constrained cyclic peptides with biarylamine linkers for peptidomimetics using palladium-catalyzed intramolecular Buchwald-Hartwig C-N coupling. We have prepared a variety of di-, tri-, and tetrapeptides (16-22-membered) in good yields using this reaction.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 16952 |
| Deposited On: | 16 Nov 2010 13:16 |
| Last Modified: | 17 Feb 2011 04:31 |
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