Hosur, R. V. ; Chary, K. V. R. ; Sheth, A. ; Govil, Girjesh ; Miles, H. T. (1988) Refined procedures for accurate determination of solution structures of nucleic acids by two dimensional nuclear magnetic resonance spectroscopy Journal of Biosciences, 13 (1). pp. 71-86. ISSN 0250-5991
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Official URL: http://www.ias.ac.in/jarch/jbiosci/13/71-86.pdf
Related URL: http://dx.doi.org/10.1007/BF02832214
Abstract
New procedures have been described for accurate determination of solution structures of nucleic acids. These are two fold; new two dimensional nuclear magnetic resonance techniques and better approaches for interpretation of nuclear magnetic resonance data for structure determination purposes. The significant development in two dimensional nuclear magnetic resonance techniques for this purpose are ω1 -scaling and recording of pure phase spectra. Use ofω1-scaled correlated and nuclear Overhauser effect spectra for estimation of interproton distances and 1H-1H coupling constants has been described. Computer simulation procedures for exact determination of structure have been described. Experimental spectra demonstrating the application of new procedures have been presented.
Item Type: | Article |
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Source: | Copyright of this article belongs to Indian Academy of Sciences. |
Keywords: | Nucleic Acids; ω-scaling; 2D NMR; Computer Simulation; Inter proton Distances |
ID Code: | 16769 |
Deposited On: | 15 Nov 2010 13:18 |
Last Modified: | 17 May 2016 01:29 |
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