Ratha, B. K. ; Kanungo, M. S. (1974) Age-dependent induction of isoenzymes of tyrosine aminotransferase of the liver of the rat Mechanisms of Ageing and Development, 3 . pp. 187-190. ISSN 0047-6374
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/004763...
Related URL: http://dx.doi.org/10.1016/0047-6374(74)90015-3
Abstract
The effects of adrenalectomy, hydrocortisone and actinomycin D on the cytoplasmic (c-), mitochondrial (m-) and nuclear (n-) tyrosine aminotransferase (TAT) isoenzymes of the liver of immature (6-) and adult (35-week) male albino rats were studied. Adrenalectomy stimulates the activity of nTAT in adult rats. The activities of mTAT of immature, and of c- and mTAT of adult rats are inhibited by adrenalectomy. Hydrocortisone induces and actinomycin D inhibits the induction of the isoenzymes in adrenalectomized rats of both ages. However, the induction and inhibition are more pronounced in the adult than in the immature.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to British Society for Research on Ageing. |
| ID Code: | 16379 |
| Deposited On: | 15 Nov 2010 13:45 |
| Last Modified: | 03 Jun 2011 09:27 |
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