Koul, O. ; Kanungo, M. S. (1975) Alterations in carbonic anhydrase of the brain of rats as a function of age Experimental Gerontology, 10 (5). pp. 273-278. ISSN 0531-5565
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/053155...
Related URL: http://dx.doi.org/10.1016/0531-5565(75)90004-2
Abstract
Carbonic anhydrase is predominantly present in glial cells and hence has been used as a marker enzyme for the study of the changes in the brain during aging of the rat. The level of the enzyme increases till adulthood and then slightly decreases when expressed as units/g wet wt, units/mg protein and units/mg DNA. There is apparently no difference in the molecular structure of the enzyme of various ages. This indicates that the changes in its level observed during the life span may be due to regulatory changes occuring in the genome.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 16365 |
| Deposited On: | 15 Nov 2010 13:47 |
| Last Modified: | 03 Jun 2011 09:26 |
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