Mahendra, G. ; Kanungo, M. S. (2000) Age-related and steroid induced changes in the histones of the quail liver Archives of Gerontology and Geriatrics, 30 (2). pp. 109-114. ISSN 0167-4943
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S01674...
Related URL: http://dx.doi.org/10.1016/S0167-4943(00)00042-X
Abstract
Histones were extracted from the liver of young, adult and old Japanese quails. Both linker and core histones were found to vary with age. An extra band, H3X, was found between H2A and H4. Its level is higher in young and old birds in comparison to that of the adult. H3X shows interesting changes under steroid induction. Its level is higher in progesterone administered young birds. In adult and old birds, it is higher in progesterone treated (P) and progesterone primed estradiol administered (P+E) birds, and lower in all estradiol (E) and estradiol primed progesterone administered (E+P) birds. The relative levels of H3X in the steroid administered birds also vary with age. Such changes may influence chromatin conformation and gene expression.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Japanese quail; 17β Estradiol; Progesterone; Histones; Aging |
| ID Code: | 16343 |
| Deposited On: | 15 Nov 2010 13:49 |
| Last Modified: | 03 Jun 2011 09:01 |
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