Novel cycloaromatization in reformatsky reaction on ∝-oxoketene dithioacetals: a regioselective synthesis of substituted ethyl 2-hydroxy-6-methylthiobenzoates

Datta, Apurba ; Ila, Hiriyakkanavar ; Junjappa, Hiriyakkanavar (1988) Novel cycloaromatization in reformatsky reaction on ∝-oxoketene dithioacetals: a regioselective synthesis of substituted ethyl 2-hydroxy-6-methylthiobenzoates Tetrahedron Letters, 29 (4). pp. 497-500. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(00)80132-X

Abstract

A novel cycloaromatization reaction leading to substituted ethyl 2-hydroxy-3-methylthiobenzoates 6̲ by condensation ∝-oxoketene dithioacetals 1̲ with excess of Reformatsky reagent 2̲ from ethyl bromoacetate through intermediate dienes 3 has been reported.

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