Polarized ketene dithioacetals; 60. Synthesis of novel 6-aryl-5-bis(methylthio)methyl-3(2h)-pyridazinones

Singh, L. W. ; Ila, H. ; Junjappa, H. (1988) Polarized ketene dithioacetals; 60. Synthesis of novel 6-aryl-5-bis(methylthio)methyl-3(2h)-pyridazinones Synthesis, 1988 (1). pp. 89-90. ISSN 0039-7881

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-1988-27477

Abstract

4-Aryl-3-bis(methylthio)methylene-4-oxobutanenitriles 1a-e undergo cyclocondensation with hydrazine hydrate to give novel 6-aryl-5-bis(methylthio)methyl-3(2H)-pyridazinones 3a-e in good yields. The reaction of ketene dithioacetal 1b with hydroxylamine afforded only the open-chain amidoxime 4.

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