Cycloaromatization of methyl (e)-4-(methyllithio)-3-(1-pyrrolidinyl)-2-butenoate with α-oxoketene N,S-acetals: direct synthesis of 3,5-bis(cycloalkylamino)biphenyls

Reddy, Kethiri R. ; Ila, Hiriyakkanavar ; Junjappa, Hiriyakkanavar (1995) Cycloaromatization of methyl (e)-4-(methyllithio)-3-(1-pyrrolidinyl)-2-butenoate with α-oxoketene N,S-acetals: direct synthesis of 3,5-bis(cycloalkylamino)biphenyls Synthesis, 1995 (8). pp. 929-930. ISSN 0039-7881

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Related URL: http://dx.doi.org/10.1055/s-1995-4029

Abstract

The vinyl carbanion 2 undergoes cycloaromatization with α-oxoketene N,S-acetals 3 through 1,4-conjugate addition-elimination process to afford 3,5-diaminobiphenyls 4 in good yields.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers Inc.
Keywords:β-pyrrolidinocrotonate; α-oxoketene N,S-acetals; Bis(cycloalkylamino)biphenyls; Cycloaromatization; γ-1,4-conjugate Addition
ID Code:15364
Deposited On:13 Nov 2010 09:14
Last Modified:22 Feb 2011 08:30

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