Extrusion reactions-VIII: a facile synthesis of 4-alkyl quin azolines and 1-methyl-2-aryl-4-quinolones

Harjit Singh, ; Aggarwal, Sunil K. ; Malnotra, Nageshwar (1986) Extrusion reactions-VIII: a facile synthesis of 4-alkyl quin azolines and 1-methyl-2-aryl-4-quinolones Tetrahedron, 42 (4). pp. 1139-1144. ISSN 0040-4020

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4020(01)87519-0

Abstract

With aq. sodium hydroxide, ω - (4(3H̲ )-quinazolinylidene) acetophenones, 4b̲ (R'= H, R=Ar) or ω-(4-quinazolinyl) acetophenones 4a̲ (R'= Me, Et; R = Ar) provide 4-alkylquinazolines 6̲ but 1-methyl-4-phenacyl or phenacylidene-3H̲-quinazolinium derivatives 10a̲ or 10b̲ give N-methyl-4-quinolone derivatives 11̲.

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