Molecular characteristics of meningiomas in a cohort of Indian patients: Loss of heterozygosity analysis of chromosomes 22, 17, 14 and 10

Chacko, Geeta ; Asirvatham, JayaRuth ; Pai, Rekha ; Nehru, ArunG ; John, Jacob ; Chacko, AriG ; Muliyil, Jayaprakash (2013) Molecular characteristics of meningiomas in a cohort of Indian patients: Loss of heterozygosity analysis of chromosomes 22, 17, 14 and 10 Neurology India, 61 (2). p. 138. ISSN 0028-3886

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Official URL: https://doi.org/10.4103/0028-3886.111119

Related URL: http://dx.doi.org/10.4103/0028-3886.111119

Abstract

Though, loss of heterozygosity (LOH) at chromosome 22q is considered to be the most likely initiating event in the formation of meningiomas, LOH at other chromosomes (1, 3, 6, 9, 10, 11, 14.17, and 18) have been implicated in its progression. The aim of this study was to analyze microsatellite markers on a select set of chromosomes including, 22q, 10q, 14q, and 17p for LOH in patients with meningiomas.

Item Type:Article
Source:Copyright of this article belongs to Neurology India.
Keywords:Loss of heterozygosity; Meningioma; Microsatellite markers.
ID Code:141917
Deposited On:29 Dec 2025 10:22
Last Modified:29 Dec 2025 10:22

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