Response to: On methods of determination of homogeneous nucleation rates of protein crystals

Zukoski, C.F. ; Kulkarni, A.M. ; Dixit, N.M. (2003) Response to: On methods of determination of homogeneous nucleation rates of protein crystals Colloids and Surfaces A: Physicochemical and Engineering Aspects, 215 (1-3). pp. 137-140. ISSN 0927-7757

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Official URL: https://doi.org/10.1016/S0927-7757(02)00424-7

Related URL: http://dx.doi.org/10.1016/S0927-7757(02)00424-7

Abstract

In their letter, Galkin and Vekilov suggest that our analysis [Dixit et al., Colloids Surf. A 190, 47 (2001)] of their experimental technique [Galkin and Vekilov, J. Phys. Chem. B 103, 10965 (1999); J. Am. Chem. Soc. 122, 156 (2000)] for estimating protein crystal nucleation rates contains inconsistencies. Here, we examine their criticisms and find that our analysis does not contain inconsistencies. We conclude by restating our claim in [Dixit et al., Colloids Surf. A 190, 47 (2001)] that Galkin and Vekilov underestimate protein crystal nucleation rates by several orders of magnitude because of the way their experimental data is interpreted.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:141559
Deposited On:01 Dec 2025 11:02
Last Modified:01 Dec 2025 11:02

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