Synergistic Experimental and Theoretical Studies of Luminescent–Magnetic Ln₂Zn₆ Clusters

Abstract

The present work is part of our ongoing quest for developing functional inorganic complexes using unorthodox pyridyl–pyrazolyl-based ligands. Accordingly, we report herein the synthesis, characterization, and luminescence and magnetic properties of four 3d–4f mixed-metal complexes with a general core of Ln₂Zn₆ (Ln = Dy, Gd, Tb, and Eu). In stark contrast to the popular wisdom of using a compartmental ligand with separate islands of hard and soft coordinating sites for selective coordination, we have vindicated our approach of using a ligand with overcrowded N-coordinating sites that show equal efficiency with both 4f and 3d metals toward multinuclear cage-cluster formation. The encouraging red and green photolumiscent features of noncytotoxic Eu₂Zn₆ and Tb₂Zn₆ complexes along with their existence in nanoscale dimension have been exploited with live-cell confocal microscopy imaging of human breast adenocarcinoma (MCF7) cells. The magnetic features of the Dy₂Zn₆ complex confirm the single-molecule-magnet behavior with befitting frequency- and temperature-dependent out-of-phase signals along with an U_eff value of ∼5 K and a relaxation time of 8.52 × 10^-6 s. The Gd₂Zn₆ complex, on the other hand, shows cryogenic magnetic refrigeration with an entropy change of 11.25 J kg^-1 K^-1 at a magnetic field of 7 T and at 2 K. Another important aspect of this work reflects the excellent agreement between the experimental results and theoretical calculations. The theoretical studies carried out using the broken-symmetry density functional theory, ORCA suite of programs, and MOLCAS calculations using the complete-active-space self-consistent-field method show an excellent synergism with the experimentally measured magnetic and spectroscopic data.