Polshettiwar, Vivek ; Varma, Rajender S. (2007) Biginelli reaction in aqueous medium: a greener and sustainable approach to substituted 3,4-dihydropyrimidin-2(1H)-ones Tetrahedron Letters, 48 (41). pp. 7343-7346. ISSN 0040-4039
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Official URL: https://doi.org/10.1016/j.tetlet.2007.08.031
Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.08.031
Abstract
An environmentally benign aqueous Biginelli protocol for the synthesis of substituted 3,4-dihydropyrimidin-2(1H)-ones using polystyrenesulfonic acid (PSSA) as a catalyst has been achieved. These microwave-assisted reactions proceed efficiently in water in the absence of organic solvent, with simple filtration as the product isolation step.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 140528 |
| Deposited On: | 24 Dec 2025 09:51 |
| Last Modified: | 24 Dec 2025 09:51 |
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