Gawande, Manoj B. ; Polshettiwar, Vivek ; Varma, Rajender S. ; Jayaram, Radha V. (2007) An efficient and chemoselective Cbz-protection of amines using silica–sulfuric acid at room temperature Tetrahedron Letters, 48 (46). pp. 8170-8173. ISSN 0040-4039
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Official URL: https://doi.org/10.1016/j.tetlet.2007.09.091
Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.09.091
Abstract
A simple, facile, and chemoselective N-benzyloxycarbonylation of amines using silica–sulfuric acid that proceeds under solvent-free conditions at room temperature has been achieved. These reactions are applicable to a wide variety of primary (aliphatic and cyclic) secondary amines, amino alcohols, and heterocyclic amines.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 140527 |
| Deposited On: | 24 Dec 2025 09:51 |
| Last Modified: | 24 Dec 2025 09:51 |
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