Polshettiwar, Vivek ; Varma, Rajender S. (2008) Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles Tetrahedron Letters, 49 (5). pp. 879-883. ISSN 0040-4039
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Official URL: https://doi.org/10.1016/j.tetlet.2007.11.165
Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.11.165
Abstract
A novel one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles by condensation of acid hydrazide and triethyl orthoalkanates under microwave irradiations is reported. This green protocol was catalyzed efficiently by solid supported Nafion®NR50 and phosphorus pentasulfide in alumina (P4S10/Al2O3) with excellent yields.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 140521 |
| Deposited On: | 24 Dec 2025 09:52 |
| Last Modified: | 24 Dec 2025 09:52 |
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